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An adaptable method using human mixed tissue ratiometric controls for benchmarking performance on gene expression microarrays in clinical laboratories

BACKGROUND: Molecular biomarkers that are based on mRNA transcripts are being developed for the diagnosis and treatment of a number of diseases. DNA microarrays are one of the primary technologies being used to develop classifiers from gene expression data for clinically relevant outcomes. Microarra...

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Detalhes bibliográficos
Main Authors: Pine, P Scott, Rosenzweig, Barry A, Thompson, Karol L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103427/
https://ncbi.nlm.nih.gov/pubmed/21486464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-38
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