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Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease

BACKGROUND: We hypothesized that the frequencies of risk alleles of SNPs mediating susceptibility to cardiovascular diseases differ among populations of varying geographic origin and that population-specific selection has operated on some of these variants. METHODS: From the database of genome-wide...

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Detalhes bibliográficos
Main Authors: Ding, Keyue, Kullo, Iftikhar J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103418/
https://ncbi.nlm.nih.gov/pubmed/21507254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-55
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