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Tyrosine phosphorylation–dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis

Transient receptor potential canonicals (TRPCs) play important roles in the regulation of intracellular calcium concentration. Mutations in the TRPC6 gene are found in patients with focal segmental glomerulosclerosis (FSGS), a proteinuric disease characterized by dysregulated function of renal glome...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kanda, Shoichiro, Harita, Yutaka, Shibagaki, Yoshio, Sekine, Takashi, Igarashi, Takashi, Inoue, Takafumi, Hattori, Seisuke
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103399/
https://ncbi.nlm.nih.gov/pubmed/21471003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-12-0929
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