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Generation and characterization of peptide mimotopes specific for anti ErbB-2 monoclonal antibodies

The erbb-2 gene receptor is often over-expressed in human cancer and its overexpression is accompanied by worse prognosis. Targeting erbb-2 gene with antibodies is an effective approach to curtail the progression of erbb-2 gene-expressing cancer types. Two monoclonal antibodies, L-26 and N-12, previ...

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Détails bibliographiques
Auteurs principaux: Witsch, Esther J., Mahlknecht, Georg, Wakim, Jean, Sertchook, Rotem, Bublil, Erez, Yarden, Yosef, Sela, Michael
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103390/
https://ncbi.nlm.nih.gov/pubmed/21602175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr028
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