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The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells
Chronic lymphocytic leukemia (CLL) is a common malignancy characterized by the accumulation of B lymphocytes with an antigen-experienced activated CD19(+)CD5(+) clonal phenotype. Clinically, ∼50% of cases will behave more aggressively. Here, we investigate the role of the major B-cell transcription...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103389/ https://ncbi.nlm.nih.gov/pubmed/21551245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr027 |
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