The B lineage transcription factor E2A regulates apoptosis in chronic lymphocytic leukemia (CLL) cells

Chronic lymphocytic leukemia (CLL) is a common malignancy characterized by the accumulation of B lymphocytes with an antigen-experienced activated CD19(+)CD5(+) clonal phenotype. Clinically, ∼50% of cases will behave more aggressively. Here, we investigate the role of the major B-cell transcription...

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Detalhes bibliográficos
Main Authors: Kardava, Lela, Yang, Qi, St. Leger, Anthony, Foon, Kenneth A., Lentzsch, Suzanne, Vallejo, Abbe N., Milcarek, Christine, Borghesi, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Original Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103389/
https://ncbi.nlm.nih.gov/pubmed/21551245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxr027
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