cAMP Activates TRPC6 Channels via the Phosphatidylinositol 3-Kinase (PI3K)-Protein Kinase B (PKB)-Mitogen-activated Protein Kinase Kinase (MEK)-ERK1/2 Signaling Pathway

cAMP is an important second messenger that executes diverse physiological function in living cells. In this study, we investigated the effect of cAMP on canonical TRPC6 (transient receptor potential channel 6) channels in TRPC6-expressing HEK293 cells and glomerular mesangial cells. The results show...

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Detalhes bibliográficos
Main Authors: Shen, Bing, Kwan, Hiu-Yee, Ma, Xin, Wong, Ching-On, Du, Juan, Huang, Yu, Yao, Xiaoqiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103323/
https://ncbi.nlm.nih.gov/pubmed/21487005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210294
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