Prefoldin Subunits Are Protected from Ubiquitin-Proteasome System-mediated Degradation by Forming Complex with Other Constituent Subunits

The molecular chaperone prefoldin (PFD) is a complex comprised of six different subunits, PFD1-PFD6, and delivers newly synthesized unfolded proteins to cytosolic chaperonin TRiC/CCT to facilitate the folding of proteins. PFD subunits also have functions different from the function of the PFD comple...

Full description

Saved in:
Bibliographic Details
Main Authors: Miyazawa, Makoto, Tashiro, Erika, Kitaura, Hirotake, Maita, Hiroshi, Suto, Hiroo, Iguchi-Ariga, Sanae M. M., Ariga, Hiroyoshi
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Protein Synthesis and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103298/
https://ncbi.nlm.nih.gov/pubmed/21478150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216259
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items