Deficiency of spermatogenesis and reduced expression of spermatogenesis-related genes in prefoldin 5-mutant mice

MM-1α is a c-Myc-binding protein and acts as a transcriptional co-repressor in the nucleus. MM-1α is also PDF5, a subunit of prefoldin that is chaperon comprised of six subunits and prevents misfolding of newly synthesized nascent polypeptides. Prefoldin also plays a role in quality control against...

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Publicado en:Biochem Biophys Rep
Autores principales: Yamane, Takuya, Shimizu, Takashi, Takahashi-Niki, Kazuko, Takekoshi, Yuka, Iguchi-Ariga, Sanae M.M., Ariga, Hiroyoshi
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668561/
https://ncbi.nlm.nih.gov/pubmed/29124133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.03.005
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