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Shrinkage Estimation for Robust and Efficient Screening of Single-SNP Association from Case-control Genome-wide Association Studies

Population-based case-control design has become one of the most popular approaches for conducting genome-wide association scans for rare diseases like cancer. In this article, we propose a novel method for improving the power of the widely used single-SNP two degrees-of-freedom (2 d.f.) association...

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Bibliografski detalji
Glavni autori: Luo, Sheng, Mukherjee, Bhramar, Chen, Jinbo, Chatterjee, Nilanjan
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103068/
https://ncbi.nlm.nih.gov/pubmed/19434716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20428
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