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Shrinkage Estimation for Robust and Efficient Screening of Single-SNP Association from Case-control Genome-wide Association Studies
Population-based case-control design has become one of the most popular approaches for conducting genome-wide association scans for rare diseases like cancer. In this article, we propose a novel method for improving the power of the widely used single-SNP two degrees-of-freedom (2 d.f.) association...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103068/ https://ncbi.nlm.nih.gov/pubmed/19434716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20428 |
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