טוען...
Evaluation of Quinazoline analogues as Glucocerebrosidase Inhibitors with Chaperone activity
Gaucher disease is a Lysosomal Storage Disorder (LSD) caused by deficiency in the enzyme glucocerebrosidase (GC). Small molecule chaperones of protein folding and translocation have been proposed as a promising therapeutic approach to this LSD. Most small molecule chaperones described in the literat...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103057/ https://ncbi.nlm.nih.gov/pubmed/21250698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1008902 |
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