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Identification of a novel REV1-interacting motif necessary for DNA polymerase κ function
When a replicative DNA polymerase (Pol) is stalled by damaged DNA, a 'polymerase switch' recruits specialized translesion synthesis (TLS) DNA polymerase(s) to sites of damage. Mammalian cells have several TLS DNA polymerases, including the four Y-family enzymes (Polη, Polι, Polκ and REV1)...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103050/ https://ncbi.nlm.nih.gov/pubmed/19170759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2443.2008.01255.x |
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