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Identification of a novel REV1-interacting motif necessary for DNA polymerase κ function

When a replicative DNA polymerase (Pol) is stalled by damaged DNA, a 'polymerase switch' recruits specialized translesion synthesis (TLS) DNA polymerase(s) to sites of damage. Mammalian cells have several TLS DNA polymerases, including the four Y-family enzymes (Polη, Polι, Polκ and REV1)...

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Bibliografiske detaljer
Main Authors: Ohashi, Eiji, Hanafusa, Tomo, Kamei, Keijiro, Song, Ihnyoung, Tomida, Junya, Hashimoto, Hiroshi, Vaziri, Cyrus, Ohmori, Haruo
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103050/
https://ncbi.nlm.nih.gov/pubmed/19170759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2443.2008.01255.x
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