Mechanism of CaMKII regulation of AMPA receptor gating

The function, trafficking and synaptic signalling of AMPA receptors are tightly regulated by phosphorylation. CaMKII phosphorylates the GluA1 AMPA subunit at Ser831 to increase single channel conductance. We show for the first time that CaMKII increases the conductance of native heteromeric AMPA rec...

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Detalhes bibliográficos
Main Authors: Kristensen, Anders S., Jenkins, Meagan A., Banke, Tue G., Schousboe, Arne, Makino, Yuichi, Johnson, Richard C., Huganir, Richard, Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102786/
https://ncbi.nlm.nih.gov/pubmed/21516102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2804
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