Mechanism of CaMKII regulation of AMPA receptor gating

The function, trafficking and synaptic signalling of AMPA receptors are tightly regulated by phosphorylation. CaMKII phosphorylates the GluA1 AMPA subunit at Ser831 to increase single channel conductance. We show for the first time that CaMKII increases the conductance of native heteromeric AMPA rec...

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Bibliografiske detaljer
Main Authors:	Kristensen, Anders S., Jenkins, Meagan A., Banke, Tue G., Schousboe, Arne, Makino, Yuichi, Johnson, Richard C., Huganir, Richard, Traynelis, Stephen F.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2011
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3102786/ https://ncbi.nlm.nih.gov/pubmed/21516102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2804
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Mechanism of CaMKII regulation of AMPA receptor gating

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