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Sequence-specific interaction of alpha-beta-anomeric double-stranded DNA with the p50 subunit of NF kappa B: application to the decoy approach.

The potential use of alpha-beta-anomeric duplex oligonucleotides to inhibit transcription factor activity by the decoy approach is investigated in this report. Indeed, several alpha-beta-anomeric heteroduplexes display a sequence-specific interaction with the p50 subunit of the transcription factor...

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Detalhes bibliográficos
Main Authors: Tanaka, H, Vickart, P, Bertrand, J R, Rayner, B, Morvan, F, Imbach, J L, Paulin, D, Malvy, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310277/
https://ncbi.nlm.nih.gov/pubmed/8065920
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