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Inappropriate transcription from the 5' end of the murine dihydrofolate reductase gene masks transcriptional regulation.

Using the nuclear run-on assay we found that in proliferating cells the transcription rate in the 5' end of the murine dihydrofolate reductase (dhfr) gene was approximately ten-fold higher than in the 3' end of the gene, suggesting transcriptional attenuation within the dhfr gene. However,...

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Detalhes bibliográficos
Main Authors: Schilling, L J, Farnham, P J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310276/
https://ncbi.nlm.nih.gov/pubmed/7520569
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