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Inappropriate transcription from the 5' end of the murine dihydrofolate reductase gene masks transcriptional regulation.
Using the nuclear run-on assay we found that in proliferating cells the transcription rate in the 5' end of the murine dihydrofolate reductase (dhfr) gene was approximately ten-fold higher than in the 3' end of the gene, suggesting transcriptional attenuation within the dhfr gene. However,...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1994
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310276/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7520569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.15.3061 |
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