An Acidic Loop and Cognate Phosphorylation Sites Define a Molecular Switch That Modulates Ubiquitin Charging Activity in Cdc34-Like Enzymes

E2 ubiquitin-conjugating enzymes are crucial mediators of protein ubiquitination, which strongly influence the ultimate fate of the target substrates. Recently, it has been shown that the activity of several enzymes of the ubiquitination pathway is finely tuned by phosphorylation, an ubiquitous mech...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Papaleo, Elena, Ranzani, Valeria, Tripodi, Farida, Vitriolo, Alessandro, Cirulli, Claudia, Fantucci, Piercarlo, Alberghina, Lilia, Vanoni, Marco, De Gioia, Luca, Coccetti, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102755/
https://ncbi.nlm.nih.gov/pubmed/21637798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002056
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados