Evidence for a purifying selection acting on the β-lactamase locus in epidemic clones of methicillin-resistant Staphylococcus aureus

BACKGROUND: The β-lactamase (bla) locus, which confers resistance to penicillins only, may control the transcription of mecA, the central element of methicillin resistance, which is embedded in a polymorphic heterelogous chromosomal cassette (the SCCmec element). In order to assess the eventual corr...

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Main Authors: Milheiriço, Catarina, Portelinha, Ana, Krippahl, Ludwig, de Lencastre, Hermínia, Oliveira, Duarte C
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102608/
https://ncbi.nlm.nih.gov/pubmed/21496235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-11-76
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