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Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene

Most methicillin-resistant Staphylococcus aureus (MRSA) strains are resistant to beta-lactam antibiotics due to the presence of the mecA gene, encoding an extra penicillin-binding protein (PBP2A) that has low affinity for virtually all beta-lactam antibiotics. Recently, a new resistance determinant—...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Milheiriço, Catarina, de Lencastre, Hermínia, Tomasz, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328527/
https://ncbi.nlm.nih.gov/pubmed/28069659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02500-16
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