CD4(+) T cells support cytotoxic T lymphocyte priming by controlling lymph node input

Rapid induction of CD8(+) cytotoxic T lymphocyte (CTL) responses is critical to combat acute infection with intracellular pathogens. CD4(+) T cells help prime antigen-specific CTLs in secondary lymphoid organs after infection in the periphery. Although the frequency of naïve precursors is very low,...

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Bibliographic Details
Main Authors: Kumamoto, Yosuke, Mattei, Lisa M., Sellers, Stephanie, Payne, Geoffrey W., Iwasaki, Akiko
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102372/
https://ncbi.nlm.nih.gov/pubmed/21555577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100567108
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