Type I Diabetes-Associated Tolerogenic Properties of Interleukin-2

Type 1 Diabetes (T1D) results from insulin-producing beta cells destruction by diabetogenic T lymphocytes in humans and nonobese diabetic (NOD) mice. The breakdown of tolerance has been associated with a defect in the number and the function of naturally occurring regulatory T cells (nTreg) that are...

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Detalhes bibliográficos
Main Authors: Chentoufi, Aziz Alami, Gaudreau, Simon, Nguyen, Alex, Sabha, Mahmoud, Amrani, Abdelaziz, ElGhazali, Geyhad
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102343/
https://ncbi.nlm.nih.gov/pubmed/21647403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/289343
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