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Functional Drug Screening Assay Reveals Potential Glioma Therapeutics

Here we describe a novel functional screening assay based on bioluminescence monitoring of the naturally secreted Gaussia luciferase (Gluc) in the conditioned medium of cultured cells. Using this assay, we identified small-molecule drugs that sensitized brain tumor cells to the tumor necrosis factor...

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Bibliografiska uppgifter
Huvudupphovsmän: Badr, Christian E., Wurdinger, Thomas, Tannous, Bakhos A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102258/
https://ncbi.nlm.nih.gov/pubmed/21184646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0324
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