Oral Delivery of Meglumine Antimoniate-β-Cyclodextrin Complex for Treatment of Leishmaniasis

The need for daily parenteral administration represents one of the most serious limitations in the clinical use of pentavalent antimonials against leishmaniasis. In this work, we investigated the ability of β-cyclodextrin to enhance the oral absorption of antimony and to promote the oral efficacy of...

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Bibliographic Details
Main Authors: Demicheli, Cynthia, Ochoa, Rosemary, da Silva, José B. B., Falcão, Camila A. B., Rossi-Bergmann, Bartira, de Melo, Alan L., Sinisterra, Ruben D., Frézard, Frédéric
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC310203/
https://ncbi.nlm.nih.gov/pubmed/14693525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.1.100-103.2004
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