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Oral Delivery of Meglumine Antimoniate-β-Cyclodextrin Complex for Treatment of Leishmaniasis

The need for daily parenteral administration represents one of the most serious limitations in the clinical use of pentavalent antimonials against leishmaniasis. In this work, we investigated the ability of β-cyclodextrin to enhance the oral absorption of antimony and to promote the oral efficacy of...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Demicheli, Cynthia, Ochoa, Rosemary, da Silva, José B. B., Falcão, Camila A. B., Rossi-Bergmann, Bartira, de Melo, Alan L., Sinisterra, Ruben D., Frézard, Frédéric
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.100-103.2004
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