Structural insight into the expanded PCB-degrading abilities of a biphenyl dioxygenase obtained by directed evolution

The biphenyl dioxygenase of Burkholderia xenovorans LB400 is a multicomponent Rieske-type oxygenase (RO) that catalyzes the dihydroxylation of biphenyl and many polychlorinated biphenyls (PCBs). The structural bases for the substrate specificity of the enzyme’s oxygenase component (BphAE(LB400)) are...

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Main Authors: Kumar, Pravindra, Mohammadi, Mahmood, Viger, Jean-François, Barriault, Diane, Gomez-Gil, Leticia, Eltis, Lindsay D., Bolin, Jeffrey T., Sylvestre, Michel
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102011/
https://ncbi.nlm.nih.gov/pubmed/21073881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.009
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