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Mechanisms of pseudosubstrate inhibition of the anaphase promoting complex by Acm1
The anaphase promoting complex (APC) is a ubiquitin ligase that promotes the degradation of cell-cycle regulators by the 26S proteasome. Cdc20 and Cdh1 are WD40-containing APC co-activators that bind destruction boxes (DB) and KEN boxes within substrates to recruit them to the APC for ubiquitination...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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Nature Publishing Group
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101997/ https://ncbi.nlm.nih.gov/pubmed/21460798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.90 |
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