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Origin of bistability underlying mammalian cell cycle entry
Precise control of cell proliferation is fundamental to tissue homeostasis and differentiation. Mammalian cells commit to proliferation at the restriction point (R-point). It has long been recognized that the R-point is tightly regulated by the Rb–E2F signaling pathway. Our recent work has further d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101952/ https://ncbi.nlm.nih.gov/pubmed/21525871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.19 |
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