Origin of bistability underlying mammalian cell cycle entry

Precise control of cell proliferation is fundamental to tissue homeostasis and differentiation. Mammalian cells commit to proliferation at the restriction point (R-point). It has long been recognized that the R-point is tightly regulated by the Rb–E2F signaling pathway. Our recent work has further d...

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Bibliographic Details
Main Authors:	Yao, Guang, Tan, Cheemeng, West, Mike, Nevins, Joseph R, You, Lingchong
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2011
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3101952/ https://ncbi.nlm.nih.gov/pubmed/21525871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.19
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Origin of bistability underlying mammalian cell cycle entry

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