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Insulin-like growth factor-binding protein-2 promotes prostate cancer cell growth via IGF-dependent or -independent mechanisms and reduces the efficacy of docetaxel

BACKGROUND: The development of androgen independence, chemo-, and radioresistance are critical markers of prostate cancer progression and the predominant reasons for its high mortality. Understanding the resistance to therapy could aid the development of more effective treatments. AIM: The aim of th...

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Bibliografiske detaljer
Main Authors: Uzoh, C C, Holly, J M P, Biernacka, K M, Persad, R A, Bahl, A, Gillatt, D, Perks, C M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101905/
https://ncbi.nlm.nih.gov/pubmed/21487405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.127
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