In Vivo Imaging of Amyloid Deposition in Alzheimer’s Disease using the Novel Radioligand [(18)F]AV-45 (Florbetapir F 18)

INTRODUCTION: An [(18)F] labeled PET amyloid (Aβ) imaging agent could facilitate clinical evaluation of late-life cognitive impairment by providing an objective measure for Alzheimer’s disease (AD) pathology. Here we present the results of the first clinical trial with [(18)F]AV-45 (Florbetapir F 18...

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Detalhes bibliográficos
Main Authors: Wong, Dean F., Rosenberg, Paul B., Zhou, Yun, Kumar, Anil, Raymont, Vanessa, Ravert, Hayden T., Dannals, Robert F., Nandi, Ayon, Brašić, James R., Ye, Weiguo, Hilton, John, Lyketsos, Constantine, Kung, Hank F., Joshi, Abhinay D., Skovronsky, Daniel M., Pontecorvo, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101877/
https://ncbi.nlm.nih.gov/pubmed/20501908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.109.069088
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