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Targeted Inactivation of the Androgen Receptor Gene in Murine Proximal Epididymis Causes Epithelial Hypotrophy and Obstructive Azoospermia

The epithelial lining of the epididymal duct expresses the androgen receptor (Ar) along its entire length and undergoes rapid and profound degeneration when androgenic support is withdrawn. However, experiments involving orchidectomy with systemic testosterone replacement, and testicular efferent du...

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Detalhes bibliográficos
Main Authors: Krutskikh, Anton, De Gendt, Karel, Sharp, Victoria, Verhoeven, Guido, Poutanen, Matti, Huhtaniemi, Ilpo
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101806/
https://ncbi.nlm.nih.gov/pubmed/21084446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0768
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