Targeted Inactivation of the Androgen Receptor Gene in Murine Proximal Epididymis Causes Epithelial Hypotrophy and Obstructive Azoospermia

The epithelial lining of the epididymal duct expresses the androgen receptor (Ar) along its entire length and undergoes rapid and profound degeneration when androgenic support is withdrawn. However, experiments involving orchidectomy with systemic testosterone replacement, and testicular efferent du...

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Hlavní autoři: Krutskikh, Anton, De Gendt, Karel, Sharp, Victoria, Verhoeven, Guido, Poutanen, Matti, Huhtaniemi, Ilpo
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Reproduction-Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101806/
https://ncbi.nlm.nih.gov/pubmed/21084446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0768
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