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Post-training intrahippocampal inhibition of class I histone deacetylases enhances long-term object-location memory
Long-term memory formation involves covalent modification of the histone proteins that package DNA. Reducing histone acetylation by mutating histone acetyltransferases impairs long-term memory, and enhancing histone acetylation by inhibiting histone deacetylases (HDACs) improves long-term memory. Pr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101774/ https://ncbi.nlm.nih.gov/pubmed/21576516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.2097411 |
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