Efficacy of adenovirally expressed soluble TRAIL in human glioma organotypic slice culture and glioma xenografts

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis in malignant cells, including gliomas, and is currently in anticancer clinical trials. However, the full-length and tagged forms of TRAIL, unlike the untagged ligand (soluble TRAIL (sTRAIL)), exhibits...

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Bibliografiske detaljer
Main Authors: Liu, Y, Lang, F, Xie, X, Prabhu, S, Xu, J, Sampath, D, Aldape, K, Fuller, G, Puduvalli, V K
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101700/
https://ncbi.nlm.nih.gov/pubmed/21368892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.95
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