Dissection of Chromosome 16p12 Linkage Peak Suggests a Possible Role for CACNG3 Variants in Age-Related Macular Degeneration Susceptibility

PURPOSE. Age-related macular degeneration (AMD) is a complex disorder of the retina, characterized by drusen, geographic atrophy, and choroidal neovascularization. Cigarette smoking and the genetic variants CFH Y402H, ARMS2 A69S, CFB R32Q, and C3 R102G have been strongly and consistently associated...

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Detalhes bibliográficos
Main Authors: Spencer, Kylee L., Olson, Lana M., Schnetz-Boutaud, Nathalie, Gallins, Paul, Wang, Gaofeng, Scott, William K., Agarwal, Anita, Jakobsdottir, Johanna, Conley, Yvette, Weeks, Daniel E., Gorin, Michael B., Pericak-Vance, Margaret A., Haines, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101690/
https://ncbi.nlm.nih.gov/pubmed/21169531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-5112
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