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Tumor Necrosis Factor-α Mediates Photoreceptor Death in a Rodent Model of Retinal Detachment

PURPOSE. Photoreceptor degeneration is a major cause of visual loss in various retinal diseases, including retinal detachment (RD) and neovascular AMD, but the underlying mechanisms remain elusive. In this study, the role of TNFα in RD-induced photoreceptor degeneration was investigated. METHODS. RD...

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Main Authors: Nakazawa, Toru, Kayama, Maki, Ryu, Morin, Kunikata, Hiroshi, Watanabe, Ryou, Yasuda, Masayuki, Kinugawa, Jiro, Vavvas, Demetrios, Miller, Joan W.
Format: Artigo
Jezik:Inglês
Izdano: Association for Research in Vision and Ophthalmology, Inc. 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101673/
https://ncbi.nlm.nih.gov/pubmed/21402953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6509
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