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Emergence of Oxacillinase-Mediated Resistance to Imipenem in Klebsiella pneumoniae
Klebsiella pneumoniae strain 11978 was isolated in Turkey in 2001 and was found to be resistant to all β-lactams, including carbapenems. Cloning and expression in Escherichia coli identified five β-lactamases, including two novel oxacillinases. The β-lactamase OXA-48 hydrolyzed imipenem at a high le...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310167/ https://ncbi.nlm.nih.gov/pubmed/14693513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.1.15-22.2004 |
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