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Emergence of Oxacillinase-Mediated Resistance to Imipenem in Klebsiella pneumoniae

Klebsiella pneumoniae strain 11978 was isolated in Turkey in 2001 and was found to be resistant to all β-lactams, including carbapenems. Cloning and expression in Escherichia coli identified five β-lactamases, including two novel oxacillinases. The β-lactamase OXA-48 hydrolyzed imipenem at a high le...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Poirel, Laurent, Héritier, Claire, Tolün, Venus, Nordmann, Patrice
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693513/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.15-22.2004
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