Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation

Extracellular regulation of signaling by transforming growth factor (TGF)–β family members is emerging as a key aspect of organ formation and tissue remodeling. In this study, we demonstrate that fibrillin-1 and -2, the structural components of extracellular microfibrils, differentially regulate TGF...

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Bibliographic Details
Main Authors: Nistala, Harikiran, Lee-Arteaga, Sui, Smaldone, Silvia, Siciliano, Gabriella, Carta, Luca, Ono, Robert N., Sengle, Gerhard, Arteaga-Solis, Emilio, Levasseur, Regis, Ducy, Patricia, Sakai, Lynn Y., Karsenty, Gerard, Ramirez, Francesco
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101602/
https://ncbi.nlm.nih.gov/pubmed/20855508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201003089
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