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Proteomic Signature of Fatty Acid Biosynthesis Inhibition Available for In Vivo Mechanism-of-Action Studies

Fatty acid biosynthesis is a promising novel antibiotic target. Two inhibitors of fatty acid biosynthesis, platencin and platensimycin, were recently discovered and their molecular targets identified. Numerous structure-activity relationship studies for both platencin and platensimycin are currently...

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書誌詳細
主要な著者: Wenzel, Michaela, Patra, Malay, Albrecht, Dirk, Chen, David Y.-K., Nicolaou, K. C., Metzler-Nolte, Nils, Bandow, Julia E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101464/
https://ncbi.nlm.nih.gov/pubmed/21383089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00078-11
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