Comparison of Proteomic Responses as Global Approach to Antibiotic Mechanism of Action Elucidation

New antibiotics are urgently needed to address the mounting resistance challenge. In early drug discovery, one of the bottlenecks is the elucidation of targets and mechanisms. To accelerate antibiotic research, we provide a proteomic approach for the rapid classification of compounds into those with...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Senges, Christoph H. R., Stepanek, Jennifer J., Wenzel, Michaela, Raatschen, Nadja, Ay, Ümran, Märtens, Yvonne, Prochnow, Pascal, Vázquez Hernández, Melissa, Yayci, Abdulkadir, Schubert, Britta, Janzing, Niklas B. M., Warmuth, Helen L., Kozik, Martin, Bongard, Jens, Alumasa, John N., Albada, Bauke, Penkova, Maya, Lukežič, Tadeja, Sorto, Nohemy A., Lorenz, Nicole, Miller, Reece G., Zhu, Bingyao, Benda, Martin, Stülke, Jörg, Schäkermann, Sina, Leichert, Lars I., Scheinpflug, Kathi, Brötz-Oesterhelt, Heike, Hertweck, Christian, Shaw, Jared T., Petković, Hrvoje, Brunel, Jean M., Keiler, Kenneth C., Metzler-Nolte, Nils, Bandow, Julia E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Mechanisms of Action: Physiological Effects
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927858/
https://ncbi.nlm.nih.gov/pubmed/33046497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01373-20
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