In Vitro and In Vivo Profiles of ACH-702, an Isothiazoloquinolone, against Bacterial Pathogens

ACH-702, a novel isothiazoloquinolone (ITQ), was assessed for antibacterial activity against a panel of Gram-positive and Gram-negative clinical isolates and found to possess broad-spectrum activity, especially against antibiotic-resistant Gram-positive strains, including methicillin-resistant Staph...

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Autors principals: Pucci, Michael J., Podos, Steven D., Thanassi, Jane A., Leggio, Melissa J., Bradbury, Barton J., Deshpande, Milind
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101440/
https://ncbi.nlm.nih.gov/pubmed/21464250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01666-10
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