γH2AX foci as a measure of DNA damage: a computational approach to automatic analysis

The γH2AX focus assay represents a fast and sensitive approach for detection of one of the critical types of DNA damage – double-strand breaks (DSB) induced by various cytotoxic agents including ionising radiation. Apart from research applications, the assay has a potential in clinical medicine/path...

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Main Authors: Ivashkevich, Alesia N., Martin, Olga A., Smith, Andrea J., Redon, Christophe E., Bonner, William M., Martin, Roger F., Lobachevsky, Pavel N.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101310/
https://ncbi.nlm.nih.gov/pubmed/21216255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2010.12.015
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