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Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis and cell survival
A clustered DNA lesion, also known as a multiply damaged site, is defined as ≥ 2 damages in the DNA within 1–2 helical turns. Only ionizing radiation and certain chemicals introduce DNA damage in the genome in this non-random way. What is now clear is that the lethality of a damaging agent is not ju...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101299/ https://ncbi.nlm.nih.gov/pubmed/21185841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2010.12.010 |
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