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Effect of Glycans and GPI Anchor on Strain Dependent Conformations of Scrapie Prion Protein: Improved Purifications and IR Spectra()

Mammalian prion diseases involve conversion of normal prion protein, PrP(C), to a pathological aggregated state (PrP(res)). The 3D structure of PrP(res) is not known but infrared (IR) spectroscopy has indicated high, strain-dependent beta sheet content. PrP(res) molecules usually contain a glycophos...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Baron, Gerald S., Hughson, Andrew G., Raymond, Gregory J., Offerdahl, Danielle K., Barton, Kelly A., Raymond, Lynne D., Dorward, David W., Caughey, Byron
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101284/
https://ncbi.nlm.nih.gov/pubmed/21539311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2003907
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