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Effect of Glycans and GPI Anchor on Strain Dependent Conformations of Scrapie Prion Protein: Improved Purifications and IR Spectra()
Mammalian prion diseases involve conversion of normal prion protein, PrP(C), to a pathological aggregated state (PrP(res)). The 3D structure of PrP(res) is not known but infrared (IR) spectroscopy has indicated high, strain-dependent beta sheet content. PrP(res) molecules usually contain a glycophos...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101284/ https://ncbi.nlm.nih.gov/pubmed/21539311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2003907 |
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