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Accelerated Neuronal Cell Recovery from Botulinum Neurotoxin Intoxication by Targeted Ubiquitination

Botulinum neurotoxin (BoNT), a Category A biodefense agent, delivers a protease to motor neuron cytosol that cleaves one or more soluble NSF attachment protein receptors (SNARE) proteins involved in neurotransmission to cause a flaccid paralysis. No antidotes exist to reverse symptoms of BoNT intoxi...

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Detalhes bibliográficos
Main Authors: Kuo, Chueh-Ling, Oyler, George A., Shoemaker, Charles B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101245/
https://ncbi.nlm.nih.gov/pubmed/21629663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020352
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