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Faster than Neutral Evolution of Constrained Sequences: The Complex Interplay of Mutational Biases and Weak Selection

Comparative genomics has become widely accepted as the major framework for the ascertainment of functionally important regions in genomes. The underlying paradigm of this approach is that most of the functional regions are assumed to be under selective constraint, which in turn reduces the rate of e...

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Main Authors: Lawrie, David S., Petrov, Dmitri A., Messer, Philipp W.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101017/
https://ncbi.nlm.nih.gov/pubmed/21498884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr032
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