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Faster than Neutral Evolution of Constrained Sequences: The Complex Interplay of Mutational Biases and Weak Selection

Comparative genomics has become widely accepted as the major framework for the ascertainment of functionally important regions in genomes. The underlying paradigm of this approach is that most of the functional regions are assumed to be under selective constraint, which in turn reduces the rate of e...

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Detalhes bibliográficos
Main Authors: Lawrie, David S., Petrov, Dmitri A., Messer, Philipp W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101017/
https://ncbi.nlm.nih.gov/pubmed/21498884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr032
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