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Faster than Neutral Evolution of Constrained Sequences: The Complex Interplay of Mutational Biases and Weak Selection

Comparative genomics has become widely accepted as the major framework for the ascertainment of functionally important regions in genomes. The underlying paradigm of this approach is that most of the functional regions are assumed to be under selective constraint, which in turn reduces the rate of e...

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Autori principali: Lawrie, David S., Petrov, Dmitri A., Messer, Philipp W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101017/
https://ncbi.nlm.nih.gov/pubmed/21498884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr032
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