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Supraspinal administration of opioids with selectivity for μ-, δ- and κ-opioid receptors produces analgesia in amphibians

Previous results using an amphibian model showed that systemic and spinal administration of opioids selective for μ, δ and κ-opioid receptors produce analgesia. It is not known whether non-mammalian vertebrates also contain supraspinal sites mediating opioid analgesia. Thus, opioid agonists selectiv...

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Bibliographic Details
Main Authors: Stevens, Craig W., Rothe, Kelly S.
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100726/
https://ncbi.nlm.nih.gov/pubmed/9274924
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