Flow-dependent channel formation in clots by an erythrocyte-bound fibrinolytic agent

Studies in animal models have shown that plasminogen activators bound to erythrocytes (RBC-PA) have an extended lifetime in the circulation and are safer than free PAs. RBC-PAs incorporate into nascent thrombi, which are focally lysed from within, an attractive thromboprophylactic option. In static...

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Detaylı Bibliyografya
Asıl Yazarlar: Gersh, Kathryn C., Zaitsev, Sergei, Cines, Douglas B., Muzykantov, Vladimir, Weisel, John W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2011
Konular:
Thrombosis and Hemostasis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100703/
https://ncbi.nlm.nih.gov/pubmed/21389322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-310409
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