Validating the use of a luciferase labeled breast cancer cell line, MDA435LCC6, as a means to monitor tumor progression and to assess the therapeutic activity of an established anticancer drug, docetaxel (Dt) alone or in combination with the ILK inhibitor, QLT0267

A significant issue in drug efficacy studies is animal study design. Here we hypothesize that when evaluating new or existing therapeutics for the treatment of cancer, the location of disease burden will influence drug efficacy. To study this, female NCr nude mice were inoculated with luciferase-pos...

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Detalhes bibliográficos
Main Authors: Kalra, Jessica, Anantha, Malathi, Warburton, Corinna, Waterhouse, Dawn, Yan, Hong, Yang, Young-joo, Strut, Dita, Osooly, Maryam, Masin, Dana, Bally, Marcel B
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100631/
https://ncbi.nlm.nih.gov/pubmed/21358264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.9.15183
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