Overexpression of HER-2 in MDA-MB-435/LCC6 Tumours is Associated with Higher Metabolic Activity and Lower Energy Stress

Overexpresssion of HER-2 in the MDA-MB-435/LCC6 (LCC6(HER-2)) tumour model is associated with significantly increased hypoxia and reduced necrosis compared to isogenic control tumours (LCC6(Vector)); this difference was not related to tumour size or changes in vascular architecture. To further evalu...

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Publicat a:Sci Rep
Autors principals: Dragowska, Wieslawa H., Ginj, Mihaela, Kozlowski, Piotr, Yung, Andrew, Ruth, Thomas J., Adam, Michael J., Sossi, Vesna, Bally, Marcel B., Yapp, Donald T. T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698760/
https://ncbi.nlm.nih.gov/pubmed/26727049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18537
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