HDL mimetic peptide ATI-5261 forms an oligomeric assembly in solution that dissociates to monomers upon dilution

ATI-5261 is a 26-mer peptide that stimulates cellular cholesterol efflux with high potency. This peptide displays high aqueous solubility, despite having amphipathic α-helix structure and a broad non-polar surface. These features suggested to us that ATI-5261 may adopt a specific form in solution, h...

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Bibliographic Details
Main Authors: Zheng, Ying, Patel, Arti B., Narayanaswami, Vasanthy, Hura, Gregory L., Hang, Bo, Bielicki, John K.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100537/
https://ncbi.nlm.nih.gov/pubmed/21476522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2002955
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